Review of the treatment of nephroblastoma at the Schneider Children’s Medical Center (DMCSH).
My girl was saved from cancer in Israel. She had kidney nephroblastoma. How much time we have lost running from doctor to doctor in our country! If a friend of mine had not advised the Assuta clinic in Israel, I don’t know how our ordeals would have ended. In Israel, my daughter was completely cured, and how could it be otherwise? After all, the best doctors in the world work there. What a new, modern medical equipment there! I have never seen so many devices in any hospital in our country! Even the operation was carried out under video control and through 4 small holes. In Israel, you feel care and confidence that such highly qualified specialists will definitely get rid of the disease. God bless them! Thank you for saving my daughter.
Mom’s review of the treatment of nephroblastoma in the Israeli medical clinic Schneider.
My child got sick at the age of two. We went to Israel, and the diagnosis was confirmed there – nephroblastoma. The doctors of the Ichilov clinic prescribed a treatment, thanks to which positive results appeared very soon. I am very glad that I entrusted my child to experienced Israeli specialists!
My son and I went to Israel for nephroblastoma treatment 2 years ago. Doctors quickly diagnosed and prescribed treatment. Now my baby is healthy and happy! By the way, in addition to the high quality of medical care, the Ichilov clinic has excellent conditions for staying. It’s cozy and comfortable here.
I turned to Memorial Hospital with kidney cancer – nephroblastoma. I underwent treatment, and now I want to thank all the employees of the center for their attentive and kind attitude, high professionalism, competence, human attitude, and support. I’m very glad that I chose you.
Doctor-consultant will answer all your questions about the cost of treatment, the choice of a doctor and fully organize treatment abroad.
Member of the Board of the Medical Faculty of the University of Kocaeli.
Membership in associations:
International Society of Pediatric Oncology
Turkish Foundation for Cancer and War Research
Turkish Pediatric Oncology Group
International Society of Pediatric Oncology (SIOP);
Turkish Pediatric Oncology Group (TPOG);
Pediatric Oncology East and Mediterranean (POEM);
Turkish Medical Association (TTB)
Scientific Director of the Department of Oncology and Hematology
Expert in the treatment of tumors:
Neoplasms: neuroblastoma, Ewing’s sarcoma, Wilms tumor, brainstem glioma.
Member of international organizations:
American Association for Cancer Research (since 1998).
American Society of Clinical Oncology (ASCO) (since 1998).
International Society of Pediatric Oncology (SIOP) (since 2001).
Head of the Department of Pediatric Hemato-Oncology
Sheba Clinic’s “Best Doctor” Award
Israeli Society of Pediatric Oncology Award
Conducts research work, author of many scientific publications, and a chapter in a book (on bone marrow transplantation).
Nephroblastoma is a malignant neoplasm that develops from the tissues of the kidneys. It is mainly diagnosed in children in the first five years of life (16% in infants, another 69% in preschoolers), equally often in girls and boys. It is one of the most common and highly malignant tumors of the genitourinary system.
The outcome for a patient diagnosed with nephroblastoma is determined by several significant factors at once:
● Histological features of the tumor (determined by the results of an examination of the tissues of the removed kidney).
● Stage of oncological disease.
The early detection of cancer and timely initiation of treatment can achieve recovery in 85-95% of cases. When the tumor spreads from the kidney to the surrounding tissues, the probability of no recurrence is reduced to 60%.
Often, a neoplasm is detected by chance, when a round, soft-elastic formation in the abdomen is found in a healthy child. The germination of a malignant node in the pyelocaliceal system of the kidney can cause hematuria (the appearance of a visible admixture of blood in the urine). Compression of soft tissues by an increasing tumor leads to the addition of abdominal pain and disruption of the intestines. In the advanced stage, in addition to local ones, general symptoms characteristic of oncological diseases can also be observed: fatigue, sweating, persistent fever, and weight loss.
A favorable prognosis for nephroblastoma is possible if the child is immediately prescribed a full-fledged complex treatment. Among the most effective methods of fighting the tumor include surgical removal of the main node and metastases, radiation and chemotherapy.
A biopsy of nephroblastoma is not performed due to the high risk of cancer cells spreading throughout the body during medical procedures. The cancerous node is removed along with the affected kidney, surrounding tissues and regional lymph nodes. Large metastatic foci in the lungs and liver are removed within healthy tissues with maximum preservation of these organs. If metastases are in the phase of active growth, surgery to eliminate them is indicated only after a course of chemotherapy.
Chemotherapeutic drugs (Doxorubicin, Vincristine, Dactinomycin, Carboplatin, etc.) are prescribed in courses before and after surgical removal of the main tumor node and metastatic foci.
In cases where an unfavorable histological type of nephroblastoma is detected in a sick child, there are not completely removed or inoperable metastases and chemotherapy is prescribed simultaneously with radiation therapy.
It is carried out in cases:
● remission was not achieved after surgery and chemotherapy;
● there is a high risk of intra-abdominal metastases;
● after surgical removal and chemotherapy, metastatic foci in the lungs reappeared.
The volume of radiation therapy performed is determined on an individual basis, depending on the previously prescribed treatment and its effectiveness.
Oncologists in our domestic clinics do everything possible for their little patients. However, their opportunities are limited for a number of reasons, the main of which is insufficient funding for health care. In this regard, it is advisable to consider foreign clinics that have no problems with the purchase of the latest diagnostic and treatment equipment, and the introduction of innovative, high-tech methods of therapy.
Here are three medical centers whose specialists can be safely entrusted with the life and health of a child with nephroblastoma:
● Ichilov Clinic (Tel Aviv, Israel). There is a well-coordinated team of oncologists, nephrologists, oncohematologists, resuscitators and other specialists who can help the child cope with the disease.
● Memorial Clinic (Ankara, Turkey). The clinic has an excellent pediatric oncologist Professor Ahmet Demir who has good treatment results. Also, the medical center replaces equipment every 5 years, due to which the diagnosis and treatment of tumors, including intracranial metastases, are carried out as efficiently and carefully as possible.
Organizing a trip to a foreign clinic may seem like a complicated matter, requiring knowledge of a lot of nuances. It is much better and easier to leave this part of the work to Experts Medical specialists who will help resolve all issues that arise both at the stage of planning a trip and upon arrival at the place.