




Mustafa Aziz Hatiboglu is a Turkish neurosurgeon; professor of the Department of Neurosurgery at Bezmialem Vakif University and director of the Gamma Knife department of the same university in Istanbul. His clinical work is focused on brain tumors — gliomas and metastases. He uses modern technologies that increase the safety of surgery: awake brain surgery, when the patient talks and performs simple tasks during the operation so that the surgeon can preserve speech and motor function; intraoperative neuromonitoring and neuronavigation. For patients whose tumor is located near important functional areas of the brain, this is critically important. Separately, he performs Gamma Knife radiosurgery — a method of single-session targeted irradiation without opening the skull, which is suitable for tumors and metastases of a certain size. He conducts active scientific work in translational brain oncology: mechanisms of tumor resistance to radiation and chemotherapy, glioma stem cells, targeted therapy, liquid biopsy. He created a biobank containing tumor and blood samples from more than 250 patients, which allows for serious scientific research on his own clinical material. For a patient with a brain tumor or brain metastases, this is a clear choice: a professor from the academic department of a major private university hospital who combines modern surgery, Gamma Knife radiosurgery, and a scientific approach to treatment.
Neurosurgery. Narrow specializations: neuro-oncology (brain tumors, metastases, gliomas), Gamma Knife radiosurgery, awake brain surgery, intraoperative neuromonitoring and neuronavigation.

Bezmialem Vakif University Hospital, Istanbul is a private university hospital. For a patient with a brain tumor or brain metastases, this is a format in which academic neurosurgery and clinical practice work in one place. This is convenient for complex cases that require a multidisciplinary consultation and modern imaging.
A separate Gamma Knife department makes it possible to apply radiosurgery in cases where open surgery is undesirable due to the location of the tumor near vital brain structures. The patient receives targeted irradiation in a single session without opening the skull and can often be discharged the same or the following day.
For an international patient, this is a practical model: one academically strong center where you can undergo surgery, radiosurgery, and follow-up observation as part of one team.
