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Ziya Kalem

Gynecologist, reproductologist

4.8

6 reviews

Istanbul, Turkey

Clinical experience: over 31 years

Seda Demir

Infertility

Dr. Zia is the reason for the happiness in my family and the smile of my daughter, who has become the miracle of my life. Very attentive, experienced and sensitive doctor. After nine attempts I finally saw a positive result and now I am 26 weeks pregnant. The doctor helped me to prepare myself psychologically despite the difficulties of my case. I am glad that we have such a specialist. I have seen many doctors in Istanbul, but Ziya was the only one who managed to give me confidence in a successful result. I sincerely recommend him.

22/02/2021

Sabina Arslan

vaginismus

I was probably one of the most difficult patients. The doctor helped me deal with vaginismus, which was causing a lot of fear. He was very patient and friendly. I thank him for his help and I am glad I met him.

11/07/2021

Yasemin Hasan

Infertility

Fate brought me to Dr. Zia. I came for a consultation but stayed for treatment and the doctor assured me that I would be able to give birth and hold my baby in my arms. I am now 14 weeks pregnant. Thank you to the doctor for his care and confidence in a successful outcome. Do not waste your time and contact him.

05/04/2021

Gulhan Kara

Infertility

After four unsuccessful IVF attempts, we approached Dr. Zia for consultation. We had previously consulted renowned specialists but did not get satisfactory answers to our questions. The doctor listened to us carefully and explained all the nuances in detail. Although embryos did not take root earlier, he instilled confidence that I would be able to become a mother. Already after the first treatment we have twins. A huge thank you to him and his team.

23/03/2021

Mustafa Ozer

Infertility

We tried treatment in different clinics, but without success. We were advised to go to Dr. Ziya, and from the first appointment he gave us hope. Calmly and patiently worked on solving the problem. After a number of procedures and embryo transfer, I finally found out that I was pregnant with twins. I am very grateful to the doctor and his team.

18/03/2021

Zeynep Polat

Infertility

We came to Dr. Ziye after hearing about his success in IVF. Fortunately, we had the opportunity to meet him. Very careful in his work, does not miss little things, with a sensitive approach to patients. Thanks to his help we had a child.

22/01/2019

Gynecologist, reproductologist

Clinical experience: over 31 years

Achievements and awards

Associate Professor, Doctor of Medical Sciences.

Author of more than 60 scientific publications in leading medical journals.

Participant of international conferences in the field of reproductology and gynecology.

About the doctor

Specialization

Ziya Kalem is an experienced gynecologist and reproductologist with more than 31 years of clinical experience working at Istinye Liv University Hospital. He specializes in the treatment of infertility and female reproductive disorders, including IVF and minimally invasive surgeries.

The doctor’s specialty:

Reproductology:

Performance of in vitro fertilization (IVF)
Intracytoplasmic sperm injection (ICSI)
Intrauterine insemination
Ovulation induction

Gynecology:

Laparoscopic and hysteroscopic interventions
Treatment of chronic pelvic pain
Diagnosis and therapy of ovarian cysts
Prevention and treatment of sexually transmitted infections
Therapy of urinary tract infections
Diseases of the uterus, vagina and vulva
Treatment of vaginal candidiasis
Removal and treatment of uterine myomas
Pediatric and adolescent gynecology
Diagnosis and treatment of precancerous diseases of genital organs

Education

1981 – Medical Faculty of the University of May 19.
1988 – Specialization in Gynecology and Obstetrics, Dr. Zekay Tahir Burak Hospital, Ankara.

Postgraduate education and courses

Certification in Assisted Reproductive Technology, Ankara Center for Assisted Reproductive Technology.
2008 – Specialization in Minimally Invasive Surgery, The Global Open University.

Clinical Experience

1993 – 1995: Gynecologist at Sereflicocisar State Hospital, Ankara.
1996 – 2004: Gynecologist at Maternity Hospital, Çorum
2005 – 2006: Gynecologist in Private IVF Center, Ankara
2006 – 2012: Gynecologist in a private hospital, Çorum
2015 – 2019: Specialist in women’s health, infertility treatment and IVF at Gürgan Hospital.
2019-present: LIV Hospital of Istinje University and IVF Center of Gürgan Clinic

Scientific activities and publications

Ziya Kalem has authored more than 60 scientific publications in Scientific Reports, The Journal of Maternal-Fetal & Neonatal Medicine, Journal of the Turkish German Gynecological Association, Saudi Medical Journal and others.

He is involved in the study of reproductive medicine, researching infertility problems, mechanisms of embryonic implantation and their relationship with various factors such as endometrial status, hormonal background and other biomarkers. His main areas of research include:

Implantation failures and Assisted Reproductive Technology (ART): Kalem is investigating ways to improve embryo implantation in women with repeated failures. Among the methods he is considering are injecting granulocyte colony-stimulating factor (G-CSF) into the uterine cavity to improve implantation, and using herbal supplements such as ginger to improve fertility.
Endometrial preparation for embryo transfer cryocycles: A study of different methods of endometrial preparation has shown that the choice of natural or hormone replacement cycles has an impact on the success of cryopreservation.
Polycystic ovarian syndrome (PCOS): Kalem’s research involves the effects of drugs such as metformin and oral contraceptives on in vitro fertilization (IVF) cycles in women with PCOS. Biomarkers such as growth factors and enzymes that affect folliculogenesis are also being investigated.
Studies of inflammatory markersand growth factors: Kalem’s work shows the relationship between levels of inflammatory markers (NLR, PLR) and birth weight, and the impact of metabolic disorders on pregnancy outcomes.
Uterine suturing techniques for cesarean section: Kalem developed a suturing technique for better healing and prevention of isthmocele formation, which reduces the risk of complications in future pregnancies.
Role of micronutrients and nutrition: Research on the role of nutrients and micronutrients in pre- and post-pregnancy periods has shown their influence on neonatal weight and reproductive function in the offspring.