CeGaT Genetic Laboratory
Tubingen
, Germany
3
reviews
Price level Medium
German certificate of accreditation and information technology standards
College of American Pathologists (CAP) Accreditation Certificate
2009
year of foundation
>200
types of genetic and transcriptome analyzes
350
doctors and researches
About clinic
CeGaT Genetic Laboratory in Germany is Europe's largest company in the field of clinical genetics. It specializes in genetic research in oncology, neurology, ophthalmology, cardiology, and reproductive medicine. CeGaT is recognized as the world's leading provider of gene analysis. The laboratory performs high-quality tests, which are confirmed by CAP, CLIA, and ISO15189 certificates and accreditations, as well as participation in EMQN and CAP interlaboratory blind testing.
CeGaT Laboratory supports physicians and patients in the search for the genetic causes of rare diseases. Pharmaceutical companies are benefiting from the genetic analysis, clinical trials, and medical innovations of CeGaT.
The headquarters of CeGaT Laboratory is located in the city of Tubingen (Germany), with affiliations in Chicago (USA) and Beijing (PRC).
The founder of CeGaT Genetic Laboratory, Saskia Bishop, MD, researcher and bioinformatician, has received numerous international awards in genetic research in Parkinson's disease.
Advantages of CeGaT Laboratory in Germany
CeGaT has several advantages over other genetic laboratories. Among them:
- A wide range of tests, from prenatal diagnosis to oncogenetics. They use innovative sequencing, microarray, and PCR technologies to analyze thousands of genes associated with various syndromes and pathologies.
- Qualified specialists perform studies following strict international standards. The medical staff includes geneticists, bioinformaticians, molecular biologists, and laboratory assistants. Most physicians have a scientific degree and are engaged in scientific research and development of the author's methods of genetic diagnostics.
- Processing of results in CeGaT takes 1-10 business days, depending on the complexity of the study. The results are available electronically through a personal account on the laboratory website or by e-mail. Delivery of results by mail or courier is possible.
- Patients can receive advice on the choice of tests, interpretation of results, and treatment recommendations.
- Prices in CeGaT depend on the type and complexity of the study. At the same time, discounts and promotions are provided for specific categories of customers (students, pensioners, large families).
- It is possible to pay for tests online.
- CeGaT is responsible for the quality and accuracy of all research.
Genetic research is constantly improving and may be revised to reflect the progress of scientific evidence. In the event of such a reassessment, CeGaT Laboratory informs the attending physicians. The re-evaluated variant will be interpreted by CeGaT specialists, taking into account the patient's clinical picture. The revised medical opinion for the patient at CeGaT will be free of charge.
Capabilities of CeGaT Genetic Laboratory in Germany
More than 200 types of genetic and transcriptomic analyses are performed in German Laboratory CeGaT in various areas, including:
- Diagnosis of hereditary diseases. It includes monogenic, multifactorial, and chromosomal disorders. Specialists of CeGaT use next-generation sequencing methods to study genes associated with various syndromes and hereditary pathologies.
- Prenatal diagnosis. Structural abnormalities of the fetus are detected in only 3% of all pregnancies during a routine ultrasound examination. Non-invasive prenatal screening (NIPT), amniocentesis, chorionic biopsy, and cardiocentesis are performed at CeGaT. Analysis of fetal cells and free fetal DNA in maternal blood is available to detect chromosomal abnormalities, microdeletions, and microduplications in the fetus. The risk of severe complications in the early stages of a child's life is also examined.
- Reproductive genetics. Screening is done to identify causes of infertility, recurrent miscarriages, premature menopause, and hereditary cancers. Specialists of CeGaT examine the genes responsible for:
- for the functioning of the reproductive system;
- for an increased risk of breast, ovarian, uterine, and prostate cancer.
- Pharmacogenetics. In CeGaT, individual sensitivity to drugs is determined to prevent unwanted side effects. Genetic changes that affect the effectiveness of drugs are identified. These drugs include antidepressants, pain relievers, neuroleptics, chemotherapy drugs, anti-AIDS drugs, anti-thrombotic drugs, anesthetics, and beta-blockers.
- Oncogenetics. NGS analysis of genetic mutations, which covers over 700 tumor-associated genes and the fusion of more than 30 genes, is used. It allows doctors to make the correct diagnosis and develop the most effective treatment regimen, considering the patient's characteristics and genomic changes in cancer. Such an analysis significantly increases the chances of recovery. The oncogenetic test aims to create drugs adapted to the patient.
This helps to enhance the therapeutic effect and minimize damage to healthy tissues. In addition, a study of genes responsible for an increased risk of developing breast, ovarian, uterine, and prostate cancers is performed.
The genetic studies data in CeGaT are processed within 2-3 weeks, after which the patient receives a medical opinion. An interdisciplinary team of molecular biologists and CeGaT specialists preliminarily discusses it. In the conclusion, the recommended methods of treatment are indicated.
How May the Patient Submit for an Analysis in CeGaT Laboratory?
Patients can go to the nearest laboratory at their place of residence for blood sampling. To send material for research to CeGat, contact the doctors-coordinators of Experts Medical. To do this, leave a request on this website.
Based on the diagnostic results, Experts Medical coordinators can arrange an online consultation with a highly specialized doctor in a foreign clinic and a treatment abroad.
The best specialties of the hospital
All
Oncology
Asif Malik
5/5
Clinic: CeGaT Genetic Laboratory
Diagnosis: PCR test
I was there for a PCR test. You don’t need or get an appointment, just wait in line. It takes a while, so dress accordingly to the weather. The staff was friendly and fast. The test wasn’t as horrible as I expected. The result came after six hours. So I can recommend this place. Not sure about the parking situation, just park and hope.
Anna Und Elena Erlenbusch
5/5
Clinic: CeGaT Genetic Laboratory
Diagnosis: PCR test
Antibody test is really quick. Despite about 9 people in front of me. Got it in 15 minutes. And the gentleman who drew blood was just brilliant. I’ve had blood drawn quite a few times. But never that fast and no pain. I actually didn’t even notice it
Hubert CHoplin
5/5
Clinic: CeGaT Genetic Laboratory
Diagnosis: PCR test
Really well organized, from the websites’ details to the test as such. All available in German and English. Arrived at 3:10pm on Tuesday, I got tested 15min later. Reasonable price, results obtained digitally 6h later.
Thank you CeGaT.
Cost of diagnostics and operations
Diagnostic
| Medical genetic consultancy | 200 € | Enquire price |
| Disease-related gene-sets | 875 - 1350 € | Enquire price |
Hereditary cancer
| Colorectal Cancer | 875 - 1200 € | Enquire price |
| Gastric Cancer | 1200 € | Enquire price |
| Cowden Syndrome | 875 € | Enquire price |
| Pancreatic cancer | 1200 € | Enquire price |
| Breast and Ovarian Cancer | 1200 - 1350 € | Enquire price |
| Tumors of the Central Nervous System | 1200 € | Enquire price |
| Renal cell carcinoma | 1200 € | Enquire price |
| Prostate Cancer | 1200 € | Enquire price |
| Pheochromocytoma and Paraganglioma | 1200 € | Enquire price |
| Xeroderma pigmentosum | 875 € | Enquire price |
| Melanoma | 800 - 1200 € | Enquire price |
Somatic cancer
| Breast and Ovarian Cancer BRCA 1 / BRCA 2 | 600 - 900 € | Enquire price |
| Tumor Immuno-Oncology Analysis (TMB and MSI) | 1950 € | Enquire price |
| Somatic tumor panel for treatment decision support | 2950 € | Enquire price |
| Lung carcinoma | 1000 € | Enquire price |
| Colorectal carcinoma | 800 € | Enquire price |
| Gastrointestinal stromal tumor | 800 € | Enquire price |
| Breast-, ovarian- and pancreatic carcinoma | 800 € | Enquire price |
| Glioblastoma | 800 € | Enquire price |
Best clinic's doctors
Dr. Saskia Biskup
Geneticist, researcher and bioinformatics
Work experience:
25 years
Achievements:
In 2009, together with her husband, she founded CeGaT GmbH, which is now a leading global provider of gene analyzes for a wide variety of inquiries from medical practice, research and the pharmaceutical industry.
In 2010 she founded the Practice for Human Genetics in Tübingen, today the Center for Human Genetics.
From April 2012 to the end of 2014, Saskia Biskup was the part-time medical director responsible for the Institute for Clinical Genetics at the Olgahospital (Stuttgart Clinic).
From 2015 she then focused 100% on her work in Tübingen. Her main concern is to make diagnostics based on the latest scientific findings available to patients. In the precision medicine of tomorrow, diagnostics is the basis for individualized and targeted therapy. Human genetics plays a central role in this.
She is a Head of Praxis for Human Genetics and a member of Molecular Tumor Board in the University Clinic Tübingen.
Her own research revolves around Parkinson’s disease, and the development of new biomarkers to enable early prediction of neurodegenerative diseases. She was awarded numerous international awards for her researches.
Dr. med. Alexander Golf
hematologist
Work experience:
20 years
Achievements:
Alexander Golf is a specialist in internal medicine with an additional qualification in hematology and internal oncology, gastroenterology, palliative medicine and emergency medicine.
After gaining recognition in the field of emergency medicine and becoming a specialist in internal medicine, he returned to the Stuttgart Clinic in 2004 as a specialist in hematology and oncology and from 2005 as senior physician. There he built up the palliative medical consultation service and headed the “Geriatric Hematology and Oncology” team.
From 2005 he built up the hematology and oncology section of the Nürtingen clinic and acted as deputy head of the colon cancer center, the oncological center and the medius tumor center of the clinics in the district of Esslingen. From 2015 to 2020 he also worked as deputy head of the oncological focus.
From 2020 to 2022 he headed the medical oncology department at the University Hospital in Tübingen (UKT), worked as senior consultant in internal medicine VIII (medical oncology and pneumology) and acted as spokesman for the center for soft tissue tumors, bone tumors and GIST as well as the interdisciplinary oncology department Tumor Conference (IOK) of the CCC Stuttgart-Tübingen.
Thomas Okech
Oncologist
Work experience:
19 years
Achievements:
In 2005 he began his specialist training in hematology and oncology at the Klinikum Stuttgart, which he continued in the internal department I in the Katharinen- and Bürgerhospital.
From January 2013 he expanded his focus on complementary medicine as senior physician at the Öschelbronn Clinic. He then worked as an employed specialist in the oncology center in Stuttgart at the Liederhalle.
Since 2018 he has been the holder of half a license for specialist medical care in hematology/oncology as part of a special needs license in a joint practice with Dr. Michael Haen in Tubingen. After moving to new premises, saying goodbye to Dr. Haen’s retirement was followed by the founding of a professional practice partnership with Dr. Alexander Golf.
Dr. med. Anja Albers
Work experience:
15 years
Achievements:
Anja Albers is a specialist in internal medicine and hematology and internal oncology, palliative medicine, emergency medicine – nutritional medicine, acupuncture.
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What tests can be done at the CeGaT laboratory in Germany?
The CeGaT laboratory in Germany offers a wide range of genetic tests for different purposes:
- determining the risk of hereditary diseases in an unborn child, for example, cystic fibrosis, fragile X syndrome, and spinal muscular atrophy;
- determination of factors that affect fertility: chromosomal abnormalities, genetic mutations, hormonal disorders;
- detection of chromosomal abnormalities in the fetus, including Down syndrome, Edwards, Patau;
- determining the sex and Rh factor of the fetus (by mother’s blood);
- diagnosing rare diseases that genetic mutations or chromosomal disorders may cause;
- diagnosis of hereditary syndromes associated with an increased risk of developing tumours;
- determination of mutations in cancer cells to understand the prognosis of the development of the disease and the choice of therapy;
- paternity DNA test.
What technologies are used in the CeGaT laboratory in Germany?
CeGaT specialists perform research on the latest generation equipment, which the management of CeGaT constantly invests in to improve the quality of tests. Such equipment is the following models:
Illumina NovaSeq 6000, NextSeq 550 and MiSeq sequencers that analyze up to 6 TB of DNA or RNA in 45 hours with high accuracy and sensitivity;- microarray scanners Affymetrix GeneChip Scanner 3000 and Agilent SureScan Microarray Scanner examine up to 1.8 million samples on a single microarray with high resolution and dynamic range;
- DNA and RNA isolation systems Qiagen QIAcube and QIAsymphony, process up to 96 samples per cycle;
- installations for qualitative and quantitative analysis of DNA and RNA Agilent Bioanalyzer 2100 and NanoDrop ND-1000 Spectrophotometer,
- PacBio Sequel IIe system;
- devices for various formats of PCR, RT-PCR, qPCR, and ddPCR tests.
This is the most modern and powerful genetic diagnostics equipment, allowing doctors to examine biomaterial samples and get the most accurate result within two days.
How genome sequencing is used in CeGat laboratory?
Genome sequencing is a complex study to obtain complete and accurate genetic information of an organism. Genome sequencing in CeGat is carried out for various purposes, for example:
- The study of genetic changes in cancer cells.
- Identifying biomarkers for diagnosis, prognosis, and choice of anticancer therapy regimen.
- Determining the most appropriate drugs and dosages for personalized therapy, predicting the possible risk of side effects or complications.
- Determining the causes of rare diseases that are caused by a gene mutation.
- Evaluation of the influence of genetic factors on the efficacy and safety of drugs.
- The study of pathogens, their types and strains to assess their resistance to antibiotics and other drugs.
- Comparison of the genomes of different types of living organisms, identifying similarities and differences between them.
- Definitions of the unique human genetic code.
- Establishment of kinship, origin, and ethnicity of a person.
- Development of new methods for diagnosing, treating, and preventing various diseases, evaluating their effectiveness and safety for humans.
What kind of genetic research on tumors is done in the CeGat laboratory in Germany?
The CeGaT laboratory in Germany performs various types of cancer tests that help identify genetic factors associated with the onset and development of cancer.
For example:
Diagnosis of hereditary syndromes associated with an increased risk of developing tumours. Determines the presence of mutations in the genes that control cell growth and division: BRCA1, BRCA2, MLH1, MSH2. The presence of mutations indicates an increased risk of developing breast, ovarian, and colon cancer. The analysis is aimed at preventing and treating neoplasms.- Comprehensive diagnosis of the tumour. The test analyzes the genetic profile of tumour cells and detects mutations, copy variations, structural rearrangements, and other changes in DNA. The study determines the type, stage, aggressiveness, and prognosis. It makes choosing the most effective therapy strategy possible, considering the tumour’s sensitivity or resistance to various drugs.
- Identification of neoantigens. It detects specific proteins formed due to mutations in tumour cells and can be recognized by the body’s immune system. The study is carried out to draw up an individual immunotherapy regimen aimed at destroying tumour cells using vaccines or cell therapy.
- Panel diagnostics. Analyzes specific groups of genes associated with certain types of tumours (melanoma, breast, prostate). The study helps to clarify the diagnosis, assess the prognosis and risk of relapse, and determine the presence of a hereditary predisposition to tumour diseases.
- Tumor mutation load test (TMB). Estimates the number of mutations in the DNA of cancer cells. They are performed to select the optimal form of immunotherapy and predict its results.
- Histocompatibility test (HLA). Studying the genetic code of body cells is responsible for recognizing self and foreign antigens. It is necessary to select the most compatible donor for bone marrow transplantation to avoid rejection.
According to the results of oncological tests, CeGaT specialists give a conclusion with recommendations on therapy methods and prevention.
What tests are done in CeGat to identify paternity?
A DNA test is performed at the CeGaT laboratory in Germany to identify paternity. This is the most accurate and reliable way to determine the biological relationship between father, mother, and child. DNA analysis in CeGat compares genetic markers passed from parents to children. The more matches between markers, the higher the likelihood of paternity.
After receiving DNA samples, the CeGaT laboratory analyzes them using modern sequencing and genotyping methods. The results of Dr. Segat’s DNA test are presented as a report containing information about the probability of paternity, the number of matching markers, statistical indicators, and other data. It takes up to 10 working days to do the test.
To take a paternity test, it is necessary to send samples of biomaterials of the father, mother, and child to the CeGaT laboratory. They can be obtained from saliva, blood, or other biological materials. Special kits are used to take the material which CeGaT employees provide. Biomaterial samples must be properly packaged and protected from damage and contamination. The coordinating doctors at Experts Medical will tell you in more detail about the conditions for collecting and transporting materials and arrange the entire process.
Advantages of DNA testing for establishing paternity in the CeGaT laboratory in Germany:
- DNA analysis allows you to determine paternity with a more than 99.99% probability, which is the gold standard in genetic diagnosis.
- The CeGaT laboratory has international accreditations according to CAP, CLIA, DIN EN ISO 15189, and DIN EN ISO 17025 standards, guaranteeing DNA analysis’s high quality and safety.
- The CeGaT laboratory accepts biomaterials from any country and provides the results of DNA analysis in electronic or paper form.
- CeGaT employees guarantee confidentiality and anonymity. The DNA test results will not be shared with third parties without the patient’s consent.
How can I do genetic tests in the CeGat laboratory?
There are 2 ways to submit biomaterials for genetic research at CeGaT:
- Directly in the CeGat laboratory itself. Experts Medical coordinators will help organize a trip to CeGaT. You can stay in Germany for 10 days or return home when the results are ready. In this case, you will receive the result through Experts Medical doctors.
- At the place of residence in the laboratory. Experts Medical organizes the transportation of genetic material to CeGat in accordance with the temperature regime and requirements.
It is worth considering that the CeGaT laboratory has clear conditions for the quality and transportation of the material. For some studies, CeGaT workers hand over special transport packages in which they deliver the material. Therefore, contacting the Experts Medical coordinating doctor before taking the tests is recommended for more detailed information on passing specific tests.
Based on the test results, Experts Medical organizes an online consultation with the best-specialized specialists from the world’s leading clinics for further treatment.